The project aims to build on the mRNA vaccine technology BioNTech became famous for developing, and which has been successful at preventing serious illness and death from Covid-19. Since then, we have seen that they also work in many different cancers, from lung cancer to bladder cancer. RECENT SUCCESSIn December 2022, the drug companies Moderna and Merck reported positive results with a personalised cancer vaccine. In this new personalised vaccine approach, the scientists took the patients' melanoma samples and looked at the letters in their DNA. The results from this mid-stage study showed that the addition of the personalised cancer vaccine reduced the risk of the cancer returning (or death from the cancer) by 44%, compared with the standard approach (surgery followed by anti-PD1 immunotherapy).
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