17 days ago
Medical News Today
It includes extensive metadata on 490 persons with Parkinson’s disease, the largest [Parkinson’s disease] cohort with microbiome data, and a unique cohort of 234 neurologically healthy elderly, which can be used in a wide range of studies. Consistently, studies have shown that an imbalance of gut microbiota is associated with neurodegenerative conditions, including Alzheimer’s disease, multiple sclerosis, and Parkinson’s disease. Studies have also examined the gut microbiome composition of individuals with Parkinson’s disease using fecal samples and have observed imbalances in the gut microbiome. Short-chain fatty acid-producing bacteria One of the clusters included gut bacterial species whose abundance showed the greatest increase in Parkinson’s disease and included bacteria belonging to the genera Bifidobacterium and Lactobacillus. These results indicate an increase in pathogenic microorganisms and bacterial species associated with inflammation in the gut of Parkinson’s disease patients.
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